OASIS Longitudinal

The Open Access Series of Imaging Studies (OASIS) is a project aimed at making MRI data sets of the brain freely available to the scientific community.

OASIS Longitudinal

This set consists of a longitudinal collection of 150 subjects aged 60 to 96. Each subject was scanned on two or more visits, separated by at least one year for a total of 373 imaging sessions. For each subject, 3 or 4 individual T1-weighted MRI scans obtained in single scan sessions are included. The subjects are all right-handed and include both men and women. 72 of the subjects were characterized as nondemented throughout the study. 64 of the included subjects were characterized as demented at the time of their initial visits and remained so for subsequent scans, including 51 individuals with mild to moderate Alzheimer’s disease. Another 14 subjects were characterized as nondemented at the time of their initial visit and were subsequently characterized as demented at a later visit.


In the platform 150 subjects with 373 sessions are uploaded.


Demographic and clinical measures are added as well as anatomic volumes.

  • Age
  • Gender
  • Handedness
  • Education
  • SES (Socio Economic Status)
  • MMSE (Mini-Mental State Examination)
  • CDR (Clinical Dementia Rating)
  • eTIV (Estimated total intracranial volume)
  • nWBV (Normalized whole brain volume)
  • ASF (Atlas scaling factor)

Longitudinal Data


OASIS Data Usage Agreement (DUA) should be complied.

The use of data is allowed as long as the data usage agreement is complied.

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When publishing findings that benefit from OASIS data, please include the following grant numbers in the acknowledgements section and in the associated Pubmed Central submission: P50 AG05681, P01 AG03991, R01 AG021910, P20 MH071616, U24 RR021382.

Primary publication

Marcus, DS, Fotenos, AF, Csernansky, JG, Morris, JC, Buckner, RL, 2009. Open Access Series of Imaging Studies (OASIS): Longitudinal MRI Data in Nondemented and Demented Older Adults. Journal of Cognitive Neuroscience, in press.